CV Blogger

HMB is sold to preserve lean mass, yet a 2026 meta-analysis of 13 trials in adults over 50 found no muscle benefit. Here is what the evidence does support.

Grape seed extract lowered diastolic blood pressure about 2 mmHg across 19 trials, but the bottle's 16,000 mg is seed weight, not dose. Here is the evidence.

This exact no-flush niacin ingredient failed its own placebo-controlled trial, and a 25,673-patient trial of real niacin found no heart-attack benefit either.

NIH's 35,533-man SELECT trial tested vitamin E for cancer prevention and found a 17% higher prostate cancer risk instead of the protection it aimed to show.

A standard 65 mg iron tablet already exceeds the NIH's adult limit, and federal law requires an overdose warning on every bottle. Here's what the evidence shows.

A 312-person trial found elderberry cut cold duration by two days, but this popular immune supplement also packs a vitamin D3 dose over the adult safety limit.

A 1,200 mg lecithin softgel isn't 1,200 mg of choline. Here is what NIH dietary reference data say about the real dose, the gap, and who actually needs more.

A 388,229-person NIH cohort study found high-dose supplemental calcium raised heart-disease death risk in men by 20% — but not from food, and not in women.

Does L-theanine work for stress and sleep? We examine human clinical trials, EEG brain wave studies, the 200 mg dose floor, and why it doesn't sedate you.

A 1,242-patient meta-analysis found real benefit for diabetic nerve pain at 600 mg a day — but this product's own label tops out at 480 mg. See the evidence.